Histologic Grading and Biomarkers of Ductal Carcinoma In Situ
نویسندگان
چکیده
منابع مشابه
Molecular grading of ductal carcinoma in situ of the breast.
PURPOSE Increased incidence of ductal carcinoma in situ (DCIS) associated with mammographic screening for breast cancer has emphasized the challenges of managing this condition. The aim of this study was to identify informative clinical indicators of DCIS biology by molecular profiling. EXPERIMENTAL DESIGN Areas of in situ carcinoma, atypical ductal hyperplasia, and benign epithelium were mic...
متن کاملDuctal Carcinoma In Situ Biology, Biomarkers, and Diagnosis
Ductal carcinoma in situ (DCIS) is an often-diagnosed breast disease and a known, non-obligate, precursor to invasive breast carcinoma. In this review, we explore the clinical and pathological features of DCIS, fundamental elements of DCIS biology including gene expression and genetic events, the relationship of DCIS with recurrence and invasive breast cancer, and the interaction of DCIS with t...
متن کاملDuctal carcinoma in situ.
Management of ductal carcinoma in situ (DCIS) has evolved from radical surgery to the option of a more minimally invasive approach. Data show that breast conservation surgery performed with administration of radiotherapy, like mastectomy, is feasible and safe. Because efforts to find a safe group for elimination of radiotherapy have resulted in data that conflict, radiotherapy still remains sta...
متن کاملHyperspectral Imaging and K-Means Classification for Histologic Evaluation of Ductal Carcinoma In Situ
Hyperspectral imaging (HSI) is a non-invasive optical imaging modality that shows the potential to aid pathologists in breast cancer diagnoses cases. In this study, breast cancer tissues from different patients were imaged by a hyperspectral system to detect spectral differences between normal and breast cancer tissues. Tissue samples mounted on slides were identified from 10 different patients...
متن کاملBreast Ductal Carcinoma In Situ
Ductal carcinoma in situ (DCIS) of the breast is becoming one of the most important diseases diagnosed in preventive medicine screening. The current age-adjusted incidence rate of DCIS is 32.5 per 100,000 women. For women 50–64 years of age, the incidence is approximately 88 per 100,000. Currently, for every 4 diagnoses of invasive breast cancer, there is 1 diagnosis of DCIS. Risk of DCIS is ra...
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ژورنال
عنوان ژورنال: Journal of Korean Breast Cancer Society
سال: 1998
ISSN: 1598-3641
DOI: 10.4048/jkbcs.1998.1.1.131